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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiao Yu

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Open access Sep 2026

Senescence-associated transcriptional reprogramming in the tumor immune microenvironment: Mechanistic layers and therapeutic opportunities

The tumor immune microenvironment (TIME) is a principal determinant of tumor progression, metastatic dissemination, and therapeutic response. Cellular senescence, primarily through the senescence-associated secretory phenotype (SASP), progressively reshapes the TIME toward immunosuppressive and therapy-resistant states...

Xiao Yu, Jian-Lei Xing, Xu-Dong Zhao et al. · 0 citations

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