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Author

Xiaoyu Chen

2 papers indexed here

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Review Open access Jul 2026

Unraveling the bidirectional interplay of the gut microbiota with chemotherapy and radiotherapy in colorectal cancer: from pathogenesis to probiotic interventions.

Colorectal cancer remains a leading cause of cancer-related mortality worldwide. While chemotherapy and radiotherapy serve as a cornerstone of treatment, their clinical efficacy is frequently compromised by therapeutic resistance and gastrointestinal toxicity. Accumulating evidence indicates that the gut microbiota is...

Ke Huang, Geng-Fan Liang, Lan-Fang Jiang et al. · 0 citations
Open access Aug 2026

Genistein inhibits colorectal cancer progression via regulating the LINC00355/miR-150/SGK1 axis and downstream EGFR/PI3K/AKT and MAPK signaling pathways.

This study provides reliable experimental evidence for the development of genistein as a potential adjuvant therapeutic agent for CRC treatment by revealing that genistein dose-dependently inhibited CRC cell proliferation without obvious cytotoxicity to normal colon cells.

Xing Zhou, Jian Qin, Zhong-Wen Feng et al. · 0 citations

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