HIV-1 is one of the most serious pathogens currently threatening human health worldwide. Although antiretroviral therapy (ART) effectively suppresses HIV-1 replication, it fails to eliminate the latent reservoir of transcriptionally silent proviruses that persist in long-lived cells, making HIV-1 latency the major obst...
Shu-Han Yang, Jin-Song Yuan, Xiao-Dong Sun et al.· Frontiers in Cellular and In...· 0 citations
Biliary tract cancers mortality among US adults aged ≥ 35 years increased from 1999 to 2023, with demographic, geographic, urbanization-related, and subtype-specific heterogeneity supported, and these findings support subtype-aware surveillance, early detection, and equitable resource allocation.
Mortality coded to ICC increased substantially in the United States from 1999 through 2024, with marked heterogeneity by sex, age, race and ethnicity, and geography.