Author

Xiaoguang Zhang

2 papers indexed here

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Open access Aug 2026

Neonatal sevoflurane exposures induced cognitive impairment via Satb2-mediated synaptic deficits

It is suggested that decreased Satb2 may contribute to cognitive disorders by reducing PSD95 levels, resulting in synaptic deficits, and lentivirus (LV)-induced Satb2 overexpression partially restored the decreases in PSD95, spine density, spontaneous alternation ratio, recognition index, the entries, and duration in n...

Jie Fang, Jichuan Zhou, Ning Huang et al. · BMC Anesthesiology · 0 citations

Clinical trial Open access Aug 2026

Postoperative Delirium After Dexmedetomidine versus Propofol Sedation in Older Adults Undergoing Hip Fracture Surgery with Spinal Anesthesia: A Randomized Controlled Trial

Purpose Postoperative delirium is a prevalent complication in elderly surgical patients and is associated with adverse outcomes, including prolonged hospitalization and long-term cognitive impairment. Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, has pharmacological properties that suggest it may...

Li Zhang, Zhongxue Su, Xiaoguang Zhang · Drug Design, Development and... · 0 citations