Open access
Sep 2026
A Clonidine-Associated α-Adrenergic Hypothesis in Sleep Bruxism Pharmacotherapy: An Evidence-Anchored Target Analysis.
BACKGROUND Sleep bruxism (SB) is a centrally regulated, arousal-related motor behaviour, but no pharmacotherapy has demonstrated reliable clinical efficacy. This study aimed to identify pathway-level signals most consistently supported by current polysomnography (PSG)-based pharmacotherapy evidence for SB. METHODS We...
De-Shui Li, Shan-Liang Sun, Hui Chen et al.
· Journal of Oral Rehabilitati... · 0 citations