Author

Xiaojin Xu

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Oct 2026

WTAP/YTHDC1-mediated m6A modification of P4HA1 suppresses hepatic gluconeogenesis and ameliorates MASLD by activating AKT signaling.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global metabolic epidemic with limited therapeutic options. Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) has been implicated in glucose metabolism, but its functional role and regulatory mechanisms in MASLD remain unknown. In this study, we establish...

Xia Cai, Xiao-Jin Xu, Mo-Ran Zhang et al. · Cellular Signalling · 0 citations

Aug 2026

Salvianolic acid a alleviates myocardial ischemia-reperfusion injury in rats via SIRT1-mediated inhibition of oxidative stress and inflammation.

SAA mitigates MIRI-induced oxidative stress and inflammation by activating SIRT1, which regulates the PGC-1α/Nrf2/HO-1 and NF-κB pathways, supporting SAA as a potential therapeutic agent for MIRI.

Zhen Chen, Yan-Ran Cao, Hao Bo et al. · International Immunopharmaco... · 0 citations