Integrating network toxicology and transcriptomics to identify CXCL8, EGFR, PTPRC, MYC, and AKT1 as key targets of microplastic-induced miscarriage
Miscarriage, a prevalent adverse pregnancy outcome linked to maternal-fetal immune dysregulation, is increasingly suspected to be influenced by environmental microplastics, although specific molecular mechanisms remain elusive. This study integrated network toxicology, transcriptomics, and molecular dynamics simulation...