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Author

Xiaolu Wei

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Open access Aug 2026

The splicing kinase PRPF-4 is required for somatic development and germline function in C. elegans

The in vivo function of the conserved spliceosomal kinase PRPF-4 in C. elegans is investigated to establish PRPF-4 as a central regulator of RNA metabolism and demonstrate the far-reaching effects on gene expression caused by loss of core splicing components.

W. Barron, Xiaolu Wei, Sakia Ferdousy et al. · 0 citations
Open access Aug 2026

Disruption of small RNAs and mechanistic variation in Segregation Distorter: A sperm-killing drive system in Drosophila melanogaster

Meiotic drivers achieve biased transmission to the next generation, often at the expense of their host. Drive is widespread and can shape the evolution of proteins, chromosome structure, and karyotypes. The sperm killer Segregation Distorter (SD) in Drosophila melanogaster is a well-studied driver but like most complex...

Logan T. Edvalson, Xiaolu Wei, Ching-Ho Chang et al. · 0 citations

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