Review
Open access
Aug 2026
Lactylation at the crossroads: Bridging metabolic rewiring and ferroptotic vulnerability in cancer
It is proposed that histone and non-histone lactylation serves as the critical “epigenetic bridge” coupling metabolic flux to ferroptosis evasion, offering a rational strategy to re-sensitize refractory tumors to ferroptosis-inducing therapies.
Ya-Li Liu, Qiang Yang, Xiaoqiang Wang et al.
· Redox Biology · 1 citation