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Xiaoru Hu

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Aug 2026

Klf5 Is Upregulated via NF-kB to Promote Maladaptive Kidney Repair and CKD Progression.

BACKGROUND Maladaptive repair following acute kidney injury leads to CKD, but the underlying molecular drivers remain incompletely understood. Krüppel-like factor 5 (Klf5), a zinc finger transcription factor, is upregulated in kidney diseases. However, its role and regulation in post-injury kidney repair are unknown....

Zhengwei Ma, Xiaoru Hu, S. Manicassamy et al. · 0 citations

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