Author

Xin-An Zhu

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Review Open access Jul 2026

Pharmacological Effects and Molecular Mechanisms of Lignans in the Treatment of Alzheimer’s Disease

This review provides a systematic synthesis of the anti-AD pharmacological mechanisms underlying nine structurally distinct lignan subtypes, emphasizing scaffold-dependent structure–activity relationships and addresses key pharmacokinetic limitations such as low oral bioavailability, rapid metabolism, and limited brain...

Li-Meng Sun, Xin-An Zhu, Chun-Yan Fan et al. · Molecules · 1 citation

Jul 2026

Mechanistic and functional study of lncRNA SNHG3/miR-128-3p/UBR5 axis in neuroinflammation in Alzheimer's disease.

This study is the first to elucidate that SNHG3 could regulate microglial polarization and neuroinflammation through the SNHG3/miR-128-3p/UBR5 axis.

Xin-An Zhu, Huijie Lu, Yumei Liu et al. · The journals of gerontology.... · 0 citations