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Xin Chen

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Open access Oct 2026

Age-based outcomes of antiretroviral therapy for people living with HIV in current follow-up: a comparative retrospective cohort study, Ganzhou, China, 2001-2021.

BACKGROUND The increasing population of elderly people living with HIV (PLHIV) presents new challenges for HIV management, while few studies have explored antiretroviral therapy (ART) effects in this population. This study aimed to compare ART outcomes across multiple physiological systems between young and elderly PLH...

Chao-Xian Lian, Ya-Lan Wu, Yi-Lin Qin et al. · 0 citations
Open access Aug 2026

Calycosin targets the MAPK-EGR1 signaling axis to inhibit enterovirus 71 replication in cells and human colonic organoids

It is shown that early growth response 1 (EGR1) is independently regulated by each of the three classical MAPK branches including extracellular signal-regulated kinase (ERK), p38 and c-Jun N-terminal kinase (JNK), and serves as a common downstream target of these pathways to promote EV71 replication and virus-induced c...

Yue Liu, Jiale Wang, Xin Chen et al. · 0 citations

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