To summarize the clinical manifestations, ancillary examination findings, treatment course, and prognosis of a patient with neurexin-3α IgG-mediated autoimmune encephalitis presenting with prominent psychiatric disturbances and choreiform movements, and to review the literature on the clinical spectrum of this dise...
Han-Yao Shen, Xin Chen, Run-Ze Yu et al.· Frontiers in Immunology· 0 citations
Current mechanistic insights inspire targeted therapeutic strategies comprising α-synuclein inhibitors, mitochondrial protectants, anti-inflammatory agents, and novel cell death pathway blockers, alongside gut-brain axis interventions for PD, but these approaches face substantial challenges.
This review systematically elaborates on the key pathological roles and molecular mechanisms of ERS and the triggered UPR in Parkinson's disease and discusses various intervention approaches, their research progress, and associated challenges.
Xin Chen, Zihao Zhao, Xinlei Yao et al.· Biochemical Pharmacology· 6 citations
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