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Sep 2026

Secretory expression of tetrameric neuraminidase enhanced by signal peptide optimization elicits robust immunity against influenza infection in mice.

An optimized signal peptide, opt-sp, is developed by introducing valine and asparagine residues at the N-terminus of the Gaussia luciferase signal peptide (Gluc-sp) and incorporating a measles virus phosphoprotein-derived tetramerization domain to identify a promising signal peptide candidate for improving recombinant...

Li-Sha Deng, Xian-Miao Ye, Xin Chen et al. · 0 citations

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