Astragaloside IV in hepatocellular carcinoma: repolarizing macrophages to reprogram the tumor microenvironment
The establishment of an immunosuppressive tumor microenvironment (TME) represents a central mechanism underlying the failure of conventional therapies and resistance to immunotherapy in hepatocellular carcinoma (HCC). Tumor-associated macrophages (TAMs), as the most abundant immune cell population within this microenvi...