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Open access Sep 2026

Ginsenoside Rg5 mitigates adenine-induced renal fibrosis by regulating the SIRT7/NETs/NLRP3 pyroptosis axis.

This study examined the protective effects of Rg5 against renal fibrosis and elucidated its underlying immunomodulatory mechanisms. A mouse model of renal fibrosis was generated through adenine administration, and Rg5 was administered orally to assess its preventative effects. Renal tubular epithelial cells (RTECs, HK-...

Jiang-Tao Zhong, Zi-Yi Xu, Ze-Long Wang et al. · 0 citations
Review Aug 2026

Anti-Inflammatory Effects of Ginsenosides: Molecular Mechanisms and Network Pharmacology Analysis.

Inflammation is a pathological process central to many chronic diseases. Conventional anti-inflammatories, including NSAIDs and corticosteroids, are limited by adverse effects and suboptimal efficacy with long-term use. Ginsenosides from Panax ginseng have emerged as promising multi-target candidates with favorable saf...

Bao-Nian Huang, Xin Guo, Yu-Min Wang et al. · 0 citations

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