Background Diabetic retinopathy (DR), a common microvascular complication of diabetes, is increasingly viewed as a systemic disorder involving the retina–brain axis. Although neuroimaging studies have reported brain abnormalities in DR, large-scale network reorganization and its biological substrates remain unclear. Me...
Die Hu, Rui-Yang Hu, Yu-Yue Cheng et al.· Diabetes, Metabolic Syndrome...· 0 citations
BACKGROUND
Anterior ischemic optic neuropathy (AION) is primarily an optic nerve disorder, but loss of visual afferent input may also be associated with cortical reorganization. Intrinsic neural timescale (INT), derived from resting-state fMRI, indexes the temporal persistence of BOLD activity. We examined whether AION...
Xiao-Nan Zhang, Xi-Long Zhang, Yuan-Zhi He et al.· Neuroscience· 0 citations
The findings provide a molecular framework for understanding post-stroke neural network reorganization and offer a link between functional neuroimaging phenotypes and gene expression, though all associations remain correlational and require mechanistic validation.
Ri-Bo Chen, Yu-Xuan He, Xin Huang et al.· Frontiers in Cellular Neuros...· 0 citations
BACKGROUND
Primary angle-closure glaucoma (PACG) damages retinal ganglion cells (RGCs) and is associated with neurodegeneration. This study used resting-state functional magnetic resonance imaging (fMRI) to analyze hemispheric lateralization and cooperative functional alterations in PACG. Machine learning assessed the...
Jing-Wen Qiu, Yuan-Zhi He, Si-Xian Li et al.· Neuroscience· 0 citations
Post-stroke alterations in intrinsic neural timescales (INTs) are investigated by combining resting-state fMRI, spatial transcriptomics, and PET-based neurochemical mapping to highlight molecular pathways and neurotransmitter systems that may constrain temporal integration and recovery potential.
Shao-Gao Gui, Zhan-Xiang Hu, Yuan-Zhi He et al.· Brain Research· 0 citations
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