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Author

Xin-Kai Qu

2 papers indexed here

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Open access Sep 2026

Myf5 Progenitors Define the Lineage Identity of Somitic Vascular Smooth Muscle Cells

Vascular smooth muscle cell (VSMC) heterogeneity drives region-specific aortic pathologies, yet the roles of somite-derived lineages remain unclear. Utilizing Myf5 and MyoD lineage tracing alongside a smooth muscle-specific Myf5 conditional knockout model, we show that Myf5-derived cells selectively populate the thorac...

Dong-Hua Hu, Kun Chen, Xi-Feng Chang et al. · 0 citations
Open access Aug 2026

DUSP1 Inhibits Mechanotransduction and MAPK Signalling to Alleviate Myocardial Cell Hypertrophy.

The findings identify a previously underappreciated role of DUSP1 in linking mechanical stress-induced signalling with MAPK activation and pathological cardiac remodelling, suggesting DUSP1 restoration as a potential therapeutic strategy for HCM-like cardiac remodelling.

Xiaoyuqian Zhong, Ling-Ran Kong, You-Jun Zhang et al. · 0 citations

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