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Open access Sep 2026

Securidaca inappendiculata Extract Mitigates Joint Damage in Collagen‐Induced Arthritis Rats Through Modulation of the SIRT1/HIF‐1α/Glycolysis Pathway

Mechanistic studies revealed that XAN attenuates inflammation by regulating the SIRT1/HIF‐1α/glycolysis signaling axis in macrophages, indicating that its anti‐inflammatory activity involves modulation of cellular energy metabolism.

Yu-Yan Zhou, Yu-Yun Zhou, Ruo-Xuan Xiang et al. · 0 citations

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