Neuregulin 1 (NRG1), as a key ligand of the epidermal growth factor receptor family, plays a crucial role in the initiation, progression, and metastasis of various solid tumors by binding to human epidermal growth factor receptor 3 (HER3) and activating downstream signaling pathways. In recent years, NRG1 gene fusions...
Yue Zhao, Yuting Yong, Yuan-Shuai Li et al.· Cancer Plus· 0 citations
This work established a robust method that successfully generated induced MKs (iMKs) from human cord blood–derived CD3+ T cells, which is a more abundant source and highlighted an optimized chemical reprogramming strategy that enables efficient conversion of T cells to MKs.