Emerging Nanoscale Platforms for Precision Glycan Analysis: Molecular Fingerprinting, Nanopore Sensing, and Spatial Readouts.
Glycans present two intrinsic properties that make nanoscale analysis a necessity rather than a refinement: a microheterogeneity that arises from non-templated biosynthesis, and a structural information density that surpasses that of nucleic acids and proteins by orders of magnitude. Both demand readout at the level of...