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Open access Aug 2026

RPLP0 identified as a ferroptosis regulator in HCC through pan-cancer analysis

Background RPLP0, a ribosomal protein critical for protein biosynthesis, has emerged as a multifaceted oncoprotein through its regulation of programmed cell death (PCD) pathways. Despite its established roles in tumorigenesis, its pan-cancer relevance and ferroptosis regulatory function remains unexplored. Methods Bioi...

Zuli Wang, Shuai Chen, Bokang Yan et al. · 0 citations
Review Open access Aug 2026

Unraveling the role of glutamine metabolism in cancer: from cell death mechanisms to tumor microenvironment modulation

Glutamine, the most abundant amino acid in human serum, serves not only as a key nutrient for maintaining normal cellular biological functions but also as an essential metabolic substrate for the proliferation and survival of tumor cells. Tumor cells exhibit a pronounced characteristic of “glutamine addiction” through...

Xin Peng, Shuang Liu, Yong-Guang Tao · 0 citations

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