Xin-Ping Xu

Phenotypic heterogeneity and genetic mechanisms of phage resistance in hypervirulent carbapenem-resistant Klebsiella pneumoniae

ABSTRACT Phage resistance represents a major obstacle to the clinical application of phage therapy for multidrug-resistant bacterial pathogens. A comprehensive understanding of the phenotypic heterogeneity and molecular mechanisms underlying phage resistance is critical for deciphering bacterium-phage interactions and...

Phosphorylation-asymmetric recombinase polymerase amplification enables target-directed circularization for ultrasensitive multiplex electrochemical detection of respiratory pathogens