Author

Xin-Sheng Yao

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Open access Sep 2026

Integrative scRNA-seq and scTCR-seq analyses decode dual TCR γδ T-cell characteristics in human and mouse

Abstract The clonal selection theory of “one lymphocyte expresses one type of antigen receptor” has been challenged and complemented by the concept of dual receptor lymphocytes. However, the proportion, source, and characterization of dual TCR γδ T cells have not been determined. Using single-cell RNA plus single-cell...

Hui-Fang Wang, Yuan-Yuan Xu, Nai-Xin Cao et al. · ImmunoHorizons · 0 citations

Review Open access Sep 2026

B-Cell Immune Responses in Myocarditis: Mechanisms, B-Cell Receptor Repertoire, and Clinical Translation

Myocarditis is an inflammatory myocardial disease induced by infection, autoimmunity, or immune checkpoint inhibitor (ICI) therapy. Its immunopathogenesis has long been attributed primarily to T-cell-mediated cellular immunity. Increasing evidence now indicates that B cells contribute to the initiation, persistence, an...

Xi-Xiong Lin, Xin-Sheng Yao, Jun Li · Cells · 0 citations