Author

Xin-Ting Li

2 papers indexed here

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Open access Oct 2026

Programming N-linked glycan composition through de novo protein design

N-linked glycans are ubiquitous post-translational modifications that mediate diverse biological processes, including cell signaling and adhesion, molecular recognition, and host-pathogen interactions. Despite their importance, N-linked glycans have largely remained beyond the reach of biomolecular design due to a lack...

Margaret C. Lunn-Halbert, J. D. Allen, Rohith Krishna et al. · bioRxiv · 0 citations

Open access Sep 2026

Computational design of potent, broadly neutralizing anti-Nipah virus and Hendra virus miniproteins

The prototype members of the genus Henipavirus, Nipah virus (NiV) and Hendra virus (HeV), cause recurrent zoonotic spillovers with case fatality rates ranging from 40-90% in humans. Currently, there are no approved vaccines or therapeutics for use in humans. Neutralizing antibodies targeting the NiV/HeV F-or G-glycopro...

J. Sims, Risako Gen, Kaitlin R. Sprouse et al. · bioRxiv · 0 citations