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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xin-Tong Yang

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Open access Aug 2026

CD38-activated macrophages drive age-related placental senescence by depleting NAD+ in decidual stromal cells

As delayed childbearing becomes increasingly common, elucidating the mechanisms of age-related placental senescence is critical for the development of effective therapeutic strategies. Here, we integrate metabolomics, single-cell RNA sequencing, and spatial transcriptomics to uncover conserved features of aged placenta...

Lun Hua, Xiao-Han Yang, Deng-Feng Gao et al. · 0 citations
Review Aug 2026

Associations of biological aging and biological age acceleration with mortality in patients with cardiorenal syndrome: A prospective cohort study.

KDM-BA, KDM-BA, PhenoAge, KDM-BAA, and PhenoAgeAccel are significantly associated with all-cause mortality among the CRS population, with a non-linear relationship observed in cerebrovascular disease.

Xin-Tong Yang, Yu-Rong Zhang, Y. Zhong et al. · 0 citations

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