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Author

Xin Wang

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Open access Jul 2026

Tumor-derived annexin A1 drives lenvatinib resistance by regulating SOX2/STAT3/S100A6 feedback loop and M2 macrophage polarization in hepatocellular carcinoma

The critical role of HCC-derived ANXA1 regulates lenvatinib resistance both intrinsically and extrinsically is demonstrated, and Targeting the SOX2/ANXA1/STAT3/S100A6 positive loop may provide a novel therapeutic strategy for HCC treatment.

Catherine Yu Jia Gu, C. Leung, R. Leung et al. · 0 citations
Open access Jul 2026

Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma

Long-read sequencing is employed to generate a high-resolution, isoform-level transcriptomic atlas from a cohort of 14 NPC tumor samples and four immortalized nasopharyngeal epithelial cell lines, and a new class of noncanonical neoantigens with significant potential for developing personalized cancer vaccines for NPC...

Yi Shuai, Hualiang Yao, Bo Wang et al. · 0 citations

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