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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xin Wang

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Review Sep 2026

Menin Inhibitors in Acute Myeloid Leukaemia: Mechanisms, Clinical Pharmacology, and Emerging Therapeutic Strategies.

Acute myeloid leukaemia (AML) remains associated with poor outcomes in relapsed or refractory disease and in molecularly defined high-risk subgroups. AML with KMT2A rearrangements (KMT2Ar) or NPM1 mutations (NPM1m) shares a dependence on the menin-KMT2A interaction, which sustains HOXA/MEIS1-driven transcription requir...

Chen-Chen Ma, Xin Wang, Jing-Yi Wang · 0 citations

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