Author

Xin-Xin Xu

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Sep 2026

Broad‐Spectrum Recombinant Antibody Profiled by Hapten Prediction and Its Application in Immunoassay for Anabolic‐Androgenic Steroids

Illegal use of anabolic‐androgenic steroids (AASs) to feed livestock can lead to food residues and endanger public health. Thus, the development of rapid, sensitive detection methods for AASs is urgently needed for AASs to safeguard food safety. In this study, four novel haptens were designed for six AASs (androstenedi...

Jia-Lin Hu, Xin-Xin Xu, Mao-Zhong Sun et al. · Small Methods · 0 citations

Oct 2026

Rational hapten design enables monoclonal antibody-based immunoassays for class-selective detection of phthalate esters in edible oils.

Phthalate esters (PAEs) are frequently detected in edible oils, necessitating rapid detection methods. However, the small molecular size and high structural similarity of PAEs make it challenging to develop antibodies that combine analytical sensitivity with group-selective recognition. Herein, a monoclonal antibody (m...

Qian-Qian Feng, Li-Qiang Liu, Ai-Hong Wu et al. · Food Chemistry · 0 citations

Sep 2026

A Dual-T-Line Immunochromatographic Assay Based on Computational Chemistry-Guided Hapten Design for Rapid On-Site Detection of Chloroneb in Agricultural and Environmental Samples

The health risks posed by chloroneb (CHL), a representative fungicide, in agricultural products and the environment necessitate rapid detection methods. Here, computational chemistry-aided rational hapten design yielded a high-performance monoclonal antibody against CHL (IC50 = 2.63 ng/mL), guided by analysis of its...

Feng He, Ling-Ling Guo, Mao-Zhong Sun et al. · Journal of Agricultural and... · 0 citations