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Xin-Xin Yi

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Open access Oct 2026

A direct RNA sequencing workflow for simultaneous profiling of tRNA abundance and modifications in mouse liver

Transfer RNA (tRNA) is highly modified and difficult to profile using reverse-transcription-based sequencing. Here, we established a direct RNA sequencing (tRNA-DRS) workflow to simultaneously characterize tRNA abundance and modification signals in mouse liver. The workflow included small-RNA enrichment, deacylation, s...

Sheng-Hong Dai, Zhao-Yang Tian, Ya-Xuan Zhang et al. · 0 citations

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