Aug 2026
Computational discovery of HIF-1α/VHL protein-protein interaction inhibitors for hypoxic cell protection.
A computational virtual-screening workflow informed by deep learning-based interface analysis is developed, supporting a computationally plausible rather than unique Cmpd16 orientation in the HIF-1α/VHL protein-protein interaction.
Bing-Lin Huang, Bi-Juan Lin, Xiao Chen et al.
· Molecular diversity · 0 citations