Author

Xin-Yan Li

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Review Open access Sep 2026

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

Metabolic reprogramming is a hallmark of many human diseases, including cancer, metabolic dysfunction, cardiovascular disease, and chronic inflammation. By reshaping bioenergetic and biosynthetic pathways, cells adapt to environmental stress and altered functional demands. Acetyl‐coenzyme A (acetyl‐CoA) plays a pivot...

Wen-Biao Wang, Xin-Yan Li, Hong-Lu Shi et al. · iNew Medicine · 0 citations

#machine learning Preprint Sep 2026

JAREX: An Acquisition Function for Multi-Objective Algorithmic Process Characterization

JAREX (Joint Acceptable Region EXploration), a Bayesian active-learning acquisition function for multi-objective process characterization, provides a modular framework for adaptive, data-efficient multi-objective algorithmic process characterization, supporting sample-efficient range finding in high-dimensional spaces.

Xin-Yan Li, Kevin Stone, A. Vikram · 0 citations