ABSTRACT Stroke remains a leading cause of long‐term neurological disability worldwide, largely due to irreversible neuronal loss and the limited regenerative capacity of the adult mammalian brain. Neural stem cells (NSCs) in the adult brain possess the potential to generate new neurons after injury, yet the molecular...
Ruo-Lin Zhang, Chang Liu, Yu-Neng Zhou et al.· Advancement of science· 0 citations
This study develops a general theory for analysing a three-dimensional (3-D) acoustofluidic system, which consists of a cavity sandwiched by parallel piezoelectric substrates. The cavity is filled with a fluid and microparticle mixture, whose movements are actuated by surface acoustic waves (SAW) generated by the piezo...
Ze-Kai Li, Yi-Ming Li, Dongfang Liang et al.· Journal of Fluid Mechanics· 0 citations
Microglia-mediated neuroinflammation is a critical contributor to cerebral ischemia/reperfusion (I/R) injury. However, the functional heterogeneity of microglia presents significant challenges in defining therapeutic signatures. By integrating single-nucleus RNA sequencing (snRNA-seq) of a mouse middle cerebral artery...