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Author

Xin-Yang Yu

2 papers indexed here

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Open access Oct 2026

Supramolecular Pretargeting Lipid Nanoparticles Based on Host-Guest Recognition Potentiate Cancer Immunotherapy by Reprogramming Tumor Microenvironment.

CN-LNPs are employed as a delivery platform to encapsulate a circular RNA encoding IL-2-Fc fusion protein, enabling intratumoral cytokine production to potentiate antitumor immunity and establish a versatile platform that overcomes the intratumoral delivery limitations commonly associated with conventional LNPs system.

Jin-Qun Gan, Yang-Fan Wang, Meng-Yao Li et al. · 0 citations
Sep 2026

Synergistic inhibition of exosome secretion and PD-L1 silence via a functional supramolecular lipid nanoparticle to boost antitumor immunity.

A chemotherapy-induced supramolecular integrated co-delivery platform that simultaneously counteracts metastasis and immunosuppression via "drug-and-gene" therapy is established, offering a promising strategy for the treatment of aggressive cancer.

Jia-Yi Men, Xue-Yan Zhang, Wen-Jie Zhang et al. · 0 citations

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