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Author

Xin-Yi Zhang

3 papers indexed here

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Oct 2026

Targeting the putative allosteric site J of cannabinoid receptor type 2 with peptide modulators: From mechanistic investigation to candidate identification.

The cannabinoid receptor type 2 (CB2) is a promising therapeutic target for neuroinflammatory diseases, whereas conventional orthosteric agonists suffer from poor selectivity and metabolic instability. Allosteric modulation, particularly by peptide-based modulators, offers a new strategy to overcome these limitations,...

Xin-Yi Zhang, Zhi-Hui Chen, Meng-Xiang Su · 0 citations
Jul 2026

Nickel-Catalyzed Enantioconvergent S N 2 O -Alkylation through Halide-Enabled Dynamic Kinetic Resolution

Metal-catalyzed enantioselective construction of C(sp 3 )–O bonds from racemic alkyl electrophiles has attracted considerable attention, yet existing approaches typically proceed through organometallic or radical intermediates. Here, we highlight a halide-enabled dynamic kinetic resolution platform that integrates rapi...

Jin-Ze Du, Xin-Yi Zhang, Yu-Li He · 0 citations
Open access Sep 2026

Ultrasensitive fluorescent biosensor for miRNA-34a detection: Magnetic separation coupled with cascade amplification of duplex-specific nuclease-assisted and hybridization chain reaction.

A highly sensitive fluorescent biosensor for miRNA-34a detection by integrating magnetic separation with cascade amplification of duplex-specific nuclease (DSN) and hybridization chain reaction (HCR) and showing excellent specificity for discriminating against interfering miRNAs is developed.

Yan-Jie Zheng, Xin-Yi Zhang, Si-Yi Wang et al. · 0 citations

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