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Review Open access Sep 2026

Matrix stiffness programs mesenchymal stromal cell immunomodulation: A mechano-epigenetic-metabolic perspective for advanced delivery systems.

The therapeutic effects of mesenchymal stromal cell (MSC)-based interventions are influenced by the biophysical characteristics of their delivery matrices and the surrounding microenvironment. While matrix stiffness is recognized as an important mechanical cue, the mechanisms linking mechanical forces to sustained immu...

Xin Yin, Ang-Di Jiao, Wen-Tong Niu et al. · 0 citations

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