Author

Xin-Yong Liu

2 papers indexed here

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Open access Sep 2026

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

Abstract This highlight summarizes the recent advances in cereblon (CRBN) substrate discovery and mechanisms of action within the field of molecular glues. It emphasizes that molecular glue technology has transitioned from the stage of monofunctional targeted protein degradation to that of rational design and multidime...

Qing-Yun Guan, Xiao-Yu Shi, Qian Yang et al. · Smart Molecules · 0 citations

Sep 2026

Small-Molecule Antivirals against Severe Fever with Thrombocytopenia Syndrome Virus: From Viral Life Cycle Targets to Host-Directed Strategies

Severe fever with thrombocytopenia syndrome virus (SFTSV), an emerging tick-borne bunyavirus with a case fatality rate of up to 30%, poses a growing threat to global public health. No approved specific antivirals are currently available. This perspective critically evaluates recent advances in the development of smal...

Zhou Tan, Ji-Wei Zhang, Chun-Hong Yin et al. · Journal of Medicinal Chemist... · 0 citations