Open access
Sep 2026
Dendritic cell centric nanoengineering couples antigen acquisition and STING activation for cancer immunotherapy.
Stimulator of interferon genes (STING) agonists have shown limited antitumor efficacy, in part because STING activation is not preferentially focused on dendritic cells (DCs), which specialize in cross-priming. We present a DC-centric strategy that synergistically licenses DCs by coordinating CD47-SIRPα checkpoint reli...
Shu-Ting Xiang, Shan-Shan Ma, Tu-Zhi Xu et al.
· Cell Reports Medicine · 0 citations