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Xin-Yu Dai

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Aug 2026

Bridging DNA damage and cGAS-STING activation: Platinum (IV) prodrugs as single-molecule chemo-immunotherapeutics.

RS-04 achieved potent tumor growth inhibition with markedly reduced systemic toxicity compared to the physical combination of its parent drugs, highlighting the clinical potential of utilizing the Pt (IV) framework as a sophisticated delivery vehicle to synchronize DNA damage with innate immune activation for superior...

Jun-Kang Ren, Jia-Ni Wu, Xin-Yu Dai et al. · 0 citations

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