Xin-Yue Chen

Nitrate-responsive Sialin2 couples stress granule assembly and clearance to maintain neuronal homeostasis.

Stress granules (SGs) are phase-separated ribonucleoprotein condensates that support cellular adaptation to acute stress, but how extracellular signals coordinate their assembly and recovery-phase clearance remains unclear. Here, we show that nitrate-responsive Sialin2 coordinates SG homeostasis across the stress cycle...