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Author

Xin-Yue Cui

2 papers indexed here

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Review Open access Oct 2026

Emerging roles of mitochondria in cancer biology: mechanisms and therapeutic targeting

Cancer remains a leading cause of global mortality, with increasing incidence and limited therapeutic options for advanced-stage disease. Accumulating evidence indicates that mitochondrial reprogramming is a key regulator of cancer biology, coordinating energy metabolism, oxidative stress, epigenetic remodeling, and...

K. Liu, Xin-Yue Cui, Li-Min Gan et al. · 0 citations
Open access Oct 2026

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

ABSTRACT Although hundreds of genes have been shown to impair fertility in animal models, the identification of corresponding genetic causes in humans remains largely unknown. Here, we identified biallelic pathogenic variants in WFS1 in three unrelated infertile men presenting with oligoasthenoteratozoospermia and fert...

Yun-Chuan Tian, Gui-Cheng Zhao, Xiang Wang et al. · 0 citations

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