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Author

Xinyue Hong

2 papers indexed here

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Open access Sep 2026

A cfDNA fragmentomics classifier for noninvasive differentiation of benign and malignant renal masses

Noninvasive differentiation of malignant and benign renal masses remains a major clinical challenge, particularly for radiologically indeterminate lesions. Here, we developed and validated a plasma cell-free DNA (cfDNA) fragmentomics-based machine learning classifier for renal mass characterization. The model was train...

Lin-Fei Li, Cong Wang, Song Wang et al. · 0 citations
Open access Aug 2026

A cfDNA fragmentomics-based liquid biopsy assay for early detection of oral cancer

Early detection of oral cancer improves outcomes, but remains limited by the invasiveness and low sensitivity of current screening methods. This study included 342 participants (200 in the training and 142 in the validation cohorts). Plasma cfDNA underwent low-depth whole-genome sequencing, with data norma...

Weiwei Wang, Tao Ding, Cuicui Liu et al. · 0 citations

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