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Xin-Yue Zhang

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Sep 2026

Inhibition of ERα in the mPFC ameliorates depression-like behaviors by suppressing GALR1-mediated synaptic dysfunction in an estrogen withdrawal-induced rat model.

Postpartum depression (PPD) is a major perinatal mood disorder closely associated with the abrupt decline in estrogen levels after childbirth. Galanin receptor1 (GALR1) is one of the receptors of galanin (GAL), which activates Gi-coupled inhibitory signaling and may play a pro-depression role. Our previous study showed...

Qian Yu, Xin-Yue Zhang, Jing-Jing Wang et al. · 0 citations

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