Author

Xin Zhang

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Sep 2026

Subpicogram-Level Quantification of Trace Biomarkers Using an Automated High-Sensitivity Chemiluminescence Immunoassay Technology Based on a Novel Substrate Enhancement Strategy

Trace biomarkers showed great potential for improving the diagnosis and monitoring of various diseases. However, the sensitivity of the current high-throughput detection platforms is limited, posing a significant challenge for the reliable measurement and clinical application of trace biomarkers. We developed an auto...

Ke-Xin Li, Zhuo-Nan Duan, Ke Li et al. · Analytical Chemistry · 0 citations

Open access Sep 2026

Age-related changes in HPT axis sensitivity and their associations with metabolic and cardiovascular health: a cross-sectional, Chinese nationwide study

Background The regulation and secretion of hormones in the endocrine system change with aging. While these changes may influence age-related disease risks, the role of hypothalamic-pituitary-thyroid (HPT) axis sensitivity in metabolic and cardiovascular health remains unclear. Methods This study enrolled 13,646 partici...

Lei Zhao, R. Mu, Xin Zhang et al. · Frontiers in Endocrinology · 0 citations