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Author

Xin-Zhe Liu

2 papers indexed here

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Open access Sep 2026

Cucurbitacin B attenuates LPS-induced skeletal muscle atrophy by inhibiting JAK2/STAT3 and suppressing proteasome activity.

BACKGROUND Skeletal muscle atrophy results from an imbalance between protein synthesis and degradation, commonly driven by chronic inflammation. Cucurbitacin B (CuB), a natural tetracyclic triterpenoid with anti-inflammatory properties, has shown therapeutic promise in various inflammatory diseases, but its role in lip...

Shen Cao, Xin-Zhe Liu, Yong Jin et al. · 0 citations
Review Open access Aug 2026

Extracellular Vesicle-Mediated Macrophage Polarization in Sepsis-Induced Acute Lung Injury: Molecular Mechanisms and Therapeutic Opportunities

Sepsis-induced acute lung injury (SI-ALI) is a severe complication of sepsis characterized by dysregulated inflammatory responses and impaired immune homeostasis. Growing evidence indicates that extracellular vesicles (EVs), particularly exosomes, are important mediators of intercellular communication. Despite the hete...

Yi-Qian Shen, Yi Tai, Xin-Zhe Liu et al. · 0 citations

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