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Findings reveal a dual oncogenic role for SETX, which represents a promising therapeutic target, as its inhibition simultaneously suppresses tumor growth and overcomes chemotherapy resistance in ovarian cancer.
Ovarian cancer is one of the most lethal gynecological malignancies globally, with significant variations in incidence, prevalence, and outcomes across regions and population subgroups. This study systematically evaluates the global, regional, and national burden of ovarian cancer from 1990 to 2021, utilizing data from...
DNM3OS acted as an independent factor for prognosis, with its low expression correlating with poor progression-free survival in CC patients, and may serve as a prognostic biomarker for CC.
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