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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Xin-Zhu Liu

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Oct 2026

Discovery of Diaryl Pyrimidine-Guanidine Derivatives as Jumonji C Domain-Containing Lysine Histone Demethylase (KDM) Inhibitors with In Vivo Anti-Cervical Cancer Activity

JMJD family histone demethylases are highly expressed in cervical cancer and promote tumor progression, highlighting their potential as therapeutic targets for this malignancy. Using a scaffold-hopping-based virtual screening, we discovered a series of diaryl pyrimidine-guanidine derivatives as KDM6B inhibitors. The...

Dong-Xuan Ni, Ting Wang, Ji-Jian Yang et al. · 0 citations

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