Review
Open access
Aug 2026
IL-37 and IL-38 in sepsis: immune-metabolic rheostats in a dynamic inflammatory continuum
Sepsis is a life-threatening syndrome driven by a dysregulated host response to infection, characterised by dynamic and overlapping phases of hyperinflammation and immune suppression. Despite advances in critical care, effective immunomodulatory therapies remain lacking, reflecting an incomplete understanding of its co...
Hai-Long Yan, Lin-Tong Ma, Xiu-Juan Huang et al.
· Frontiers in Immunology · 0 citations