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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Xinghe Wang

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Clinical trial Open access Sep 2026

Effects of Intranasal Dexmedetomidine on the Night Before Surgery on Postoperative Delirium in Elderly Patients Undergoing Total Knee/Hip Arthroplasty. A Parallel-Arm, Randomized Controlled, Non-Inferiority Trial

Importance It is crucial to identify preoperative treatment methods that can safely and effectively reduce the incidence of postoperative delirium. Objective To evaluate whether preoperative intranasal dexmedetomidine administration for preventing postoperative delirium is non-inferior to intravenous dexmedetomidine in...

Yang-Yang Chen, Ke-Qin Wang, Yu-Qi Zhang et al. · 1 citation
Review Sep 2026

The Dorsal Raphe Nucleus: A Critical Hub in the Neurocircuitry of General Anesthesia.

The dorsal raphe nucleus (DRN), the brain's primary source of serotonin, is a critical hub for regulating arousal, mood, pain, and sleep-wake cycles. Here we review what is currently known about how the DRN modulates general anesthesia. We focus on four neuronal groups, namely serotonergic, GABAergic, glutamatergic, an...

An-Yin Wang, Hui Zhou, Xing-He Wang et al. · 0 citations

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