Author

Xingpiao Jin

3 papers indexed here

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Oct 2026

Trichoxanes A and B: Molecular Networking-Guided Discovery of Cage-Like Sorbicillinoids as Mycobacterium tuberculosis GlmU Inhibitors

Trichoxanes A (1) and B (2), two novel sorbicillinoids featuring a unique cage-like 2,7-dioxa-pentacyclo[7.4.0.03,8.05,13.06,10]tridecane scaffold, were isolated from Trichoderma reesei via a molecular networking strategy. Their structures were elucidated by spectroscopic analyses, CASE, DP4+ NMR calculations, and EC...

Rui Jiang, Xin-Yu Zheng, Xing-Piao Jin et al. · Organic Letters · 0 citations

Sep 2026

Structurally diverse indole alkaloids from an endolichenic fungus Aspergillus sp. with antiproliferative activity against non-small cell lung cancer cells.

Chemical investigation of the endolichenic fungus Aspergillus sp. TJ403-YJ22 led to the isolation and characterization of twelve new indole alkaloids, asperkaloids A-L (1-12). Compounds 1-10 represent non-paspaline-type indole-diterpenoids, whereas 11 and 12 are polyketide-indole hybrids. Notably, compounds 1 and 2 pos...

Jun Yao, Xing-Piao Jin, Wei-Wei Wang et al. · Bioorganic chemistry (Print) · 0 citations

Aug 2026

Discovery of Polycyclic Polyprenylated Acylphloroglucinols from Hypericum androsaemum as Dual-Mechanism Inhibitors of Mycobacterium tuberculosis GlmU Acetyltransferase.

(±)-Hypericandrone A and (+)-1 displayed potent antitubercular activity by selectively inhibiting the acetyltransferase domain of Mycobacterium tuberculosis GlmU through a dual mechanism, acting competitively against acetyl-CoA and noncompetitively against glucosamine-1-phosphate.

Jiang-Chun Wei, Xing-Piao Jin, Xiang-Wang Zhao et al. · Organic Letters · 2 citations